Consumptive Coagulopathy as Biochemical Mechanism in Oxygen Toxicity and its Enhancement by Lead(II) Ions
نویسندگان
چکیده
منابع مشابه
Localized consumptive coagulopathy.
An 87-year-old man with an extensive past medical history was admitted for evaluation of intermittent hemoptysis of 1 month’s duration. During the hospitalization, he developed a large, subcutaneous bleed (Figure 1) after venipuncture. The patient had a known, expanding thoracic aortic aneurysm (Figures 2 and 3), and laboratory studies were consistent with an intravascular, consumptive coagulop...
متن کاملConsumptive Coagulopathy in Angiosarcoma: A Recurrent Phenomenon?
Objectives. To report the prevalence of consumptive coagulopathy in angiosarcoma patients seen at a single center. Methods. We retrospectively reviewed case records of 42 patients diagnosed with angiosarcoma at Mount Sinai Hospital between 2000 and 2013. Results. Seven patients (17%) met clinical criteria for disseminated intravascular coagulation (DIC) in absence of concomitant clinical states...
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Acute consumptive coagulopathy may be initiated by diverse events. It is frequently necessary to establish the diagnosis with urgency. Rational therapy can only be approached with knowledge of the relative impact the primary consumption exerts upon hemostasis as well as the effects of secondary fibrinolysis. A constellation of interlocking tests within the capability of the small laboratory is ...
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Acrylamide (AA) is an important industrial chemical agent that is mainly used in the production of polymers and copolymers. Recently it has been attention because of its production in the diet at high-temperature (>120 ºC) processes such as cooking, frying, toasting, roasting or baking of high carbohydrate foods. According to high exposure to acrylamide, recognition of its toxic effect is ...
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Rats given disulfiram (200 mg/kg) or diethyldithiocarbamate (200 mg/kg) by intraperitoneal injection were exposed to 2 atmospheres absolute oxygen in a hyperbaric chamber or kept in normoxia. By 12 hr of hyperoxia exposure, none of the control but 30% of the disulfiram-treated and 87% of the diethyldithiocarbamate-treated rats had died. Both disulfiram and diethyldithiocarbamate administration ...
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ژورنال
عنوان ژورنال: Clinical Chemistry and Laboratory Medicine
سال: 1977
ISSN: 1434-6621,1437-4331
DOI: 10.1515/cclm.1977.15.1-12.449